Literature
PubMed
PubMed® comprises more than 37 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.
Featured Bookshelf titles
Drugs and Lactation Database (LactMed®)
Characteristics of Existing Asthma Self-Management Education Packages
Leas BF, Tipton K, Bryant-Stephens T, et al.
Browse the Bookshelf
Literature databases
Bookshelf
Books and reports
MeSH
Ontology used for PubMed indexing
NLM Catalog
Books, journals and more in the NLM Collections
PubMed
Scientific and medical abstracts/citations
PubMed Central
Full-text journal articles
Data
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Gene
Collected information about gene loci
GEO Profiles
Gene expression and molecular abundance profiles
hom*oloGene
hom*ologous genes sets for selected organisms
PopSet
Sequence sets from phylogenetic and population studies
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved Domains
Conserved protein domains
Identical Protein Groups
Protein sequences grouped by identity
Protein
Protein sequences
Protein Family Models
Models representing hom*ologous proteins with a common function
Structure
Experimentally-determined biomolecular structures
BLAST
A tool to find regions of similarity between biological sequences
blastn
Search nucleotide sequence databases
blastp
Search protein sequence databases
blastx
Search protein databases using a translated nucleotide query
tblastn
Search translated nucleotide databases using a protein query
Primer-BLAST
Find primers specific to your PCR template
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Assembly
Genome assembly information
BioCollections
Museum, herbaria, and other biorepository collections
BioProject
Biological projects providing data to NCBI
BioSample
Descriptions of biological source materials
Genome
Genome sequencing projects by organism
Nucleotide
DNA and RNA sequences
SRA
High-throughput sequence reads
Taxonomy
Taxonomic classification and nomenclature
Clinical
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
ClinicalTrials.gov
Privately and publicly funded clinical studies conducted around the world
ClinVar
Human variations of clinical significance
dbGaP
Genotype/phenotype interaction studies
dbSNP
Short genetic variations
dbVar
Genome structural variation studies
GTR
Genetic testing registry
MedGen
Medical genetics literature and links
OMIM
Online mendelian inheritance in man
PubChem
Repository of chemical information, molecular pathways, and tools for bioactivity screening
BioAssays
Bioactivity screening studies
Compounds
Chemical information with structures, information and links
Pathways
Molecular pathways with links to genes, proteins and chemicals
Substances
Deposited substance and chemical information
News
Research news
NIH Research Matters MARCH 26, 2024
Talk therapy cuts risk of postpartum depression
An intervention given to pregnant women by non-specialist providers greatly reduced the chances of developing postpartum depression or anxiety.
NIH Research Matters MARCH 26, 2024
How excess niacin may promote cardiovascular disease
Findings about a metabolite of niacin, or vitamin B3, raise concerns about the health effects of too much niacin and suggest new measures to help prevent or treat cardiovascular disease
The Washington Post MARCH 26, 2024
Birds, bees and even plants might act weird during the solar eclipse
Carolyn Y. Johnson
A total eclipse isn’t just a spectacle in the sky. Birds, insects and even plants will take notice, and might start acting strange.
Recent blog posts
NCBI Insights MARCH 28, 2024
MedGen Users, We Want Your Feedback!
Do you use NCBI’s MedGen? If so, then you probably know it’s NCBI’s one-stop-shop for genetic phenotype information. If you are a healthcare provider, genetic professional, researcher, or anyone who uses MedGen, we want to hear from you to help us make this resource better meet your needs! We want to know: How you currently … Continue reading MedGen Users, We Want Your Feedback! →
NIH Director's Blog MARCH 28, 2024
Immune Checkpoint Discovery Has Implications for Treating Cancer and Autoimmune Diseases
Your immune system should ideally recognize and attack infectious invaders and cancerous cells. But the system requires safety mechanisms, or brakes, to keep it from damaging healthy cells. To do this, T cells—the immune system’s most powerful attackers—rely on immune “checkpoints” to turn immune activation down when they receive the right signal. While these interactions have been well studied, a research team supported in part by NIH has made an unexpected discovery into how a key immune checkpoint works, with potentially important implications for therapies designed to boost or dampen immune activity to treat cancer and autoimmune diseases.
NLM Musings MARCH 27, 2024
“Computers don’t diagnose the same way that doctors do” - NLM Lecture Explored How a Cancer Diagnosis Can Help Illustra…
How can cancer help us understand algorithmic bias? At this year’s NLM Science, Technology, and Society Lecture, journalist and AI ethics expert Meredith Broussard shared how her personal experience with breast cancer can help illuminate the potential impact that racial and gender bias can have on the use of AI in medical contexts.